In May 2023, a 72-year-outdated feminine affected person was referred to our department resulting from exertional dyspnea. On the age of 68, she began to note swelling within the hands and toes. Based on the findings of pores and skin hardening extending beyond the fingers and toes, along with consistent histopathologic findings from a skin biopsy, the rheumatology department of her earlier hospital diagnosed her as having SSc, although varied autoantibodies characteristic of scleroderma have been unfavorable. Steroid therapy (PSL 20mg/day) was initiated, and BloodVitals tracker the dosage was steadily tapered off because the cutaneous symptoms improved. Since the initiation of PSL remedy, the patient had been experiencing exertional dyspnea without apparent lung shadows (Fig.1a). Two years later, an elevated Krebs von den Lungen-6 (KL-6, 2257 U/mL) and BloodVitals tracker diffuse ground-glass opacities in the bilateral lung fields on chest computed tomography (CT) led to a prognosis of interstitial lung illness (ILD) associated with SSc (Fig.1b). Despite repeated IVCY and steroids, there was no improvement in subjective symptoms or imaging findings (Fig.1c)
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Autoimmune Pulmonary Alveolar Proteinosis Developed during Treatment for Systemic Sclerosis: A Case Report (2025)
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